The latest medical research on Ophthalmology

The research magnet gathers the latest research from around the web, based on your specialty area. Below you will find a sample of some of the most recent articles from reputable medical journals about ophthalmology gathered by our medical AI research bot.

The selection below is filtered by medical specialty. Registered users get access to the Plexa Intelligent Filtering System that personalises your dashboard to display only content that is relevant to you.

Want more personalised results?

Request Access

Transcranial near-infrared photobiomodulation could modulate brain electrophysiological features and attentional performance in healthy young adults.

Lasers in Medical Science

The aim of the present study was to investigate the electrophysiological effects of the photobiomodulation (PBM) by the quantitative electroencepha...

Effects of photobiomodulation in the treatment of fractures: a systematic review and meta-analysis of randomized clinical trials.

Lasers in Medical Science

Several therapeutic strategies have been proposed to optimize the conventional treatment of fractures. Photobiomodulation (PBM) appears to help red...

New concept for treating urinary incontinence after radical prostatectomy with radiofrequency: phase 1 clinical trial.

Lasers in Medical Science

To describe the clinical response and side effects of radiofrequency treatment in patients with urinary incontinence after radical prostatectomy. T...

Label-free diagnosis of lung cancer with tissue-slice surface-enhanced Raman spectroscopy and statistical analysis.

Lasers in Medical Science

Despite the rapid development of medical science, the diagnosis of lung cancer is still quite challenging. Due to the ultrahigh detection sensitivi...

Improved detection of subgingival calculus by laser fluorescence over differential reflectometry.

Lasers in Medical Science

Laser fluorescence (LF) and differential reflectometry (DR) are two new optical methods which have been used to help diagnose subgingival deposits ...

Effect of quality-switched laser exposure in patients with history of edible gold consumption.

Lasers in Medical Science

Injectable gold is known to deposit in the dermis for life, and such patients are at risk of developing chrysiasis post-laser exposure. It is unkno...

Ultraviolet A/blue light-emitting diode therapy for vulvovaginal candidiasis: a case presentation.

Lasers in Medical Science

Vulvovaginal candidiasis (VVC) is a frequent infection of the female genitourinary tract. It is considered the second most common genital infection...

Evaluation of nonlinear optical behavior of mouse colon cancer cell line CT26 in hyperthermia treatment.

Lasers in Medical Science

Hyperthermia treatment can induce component changes on cell. This study explored the potential of Z-scan to improve accuracy in the identification ...

Correction to: Photobiomodulation can alter mRNA levels cell death-related.

Lasers in Medical Science

The authors wish to clarify that Fávia de Paoli refers to "Flávia de Paoli". The authors apologise for this error.

Modified optical coefficient measurement system for bulk tissue using an optical fiber insertion with varying field of view and depth at the fiber tip.

Lasers in Medical Science

To measure the few millimeter-scale macroscopic optical properties of biological tissue, including the scattering coefficient, while avoiding the i...

HGF-rs12536657 and Ocular Biometric Parameters in Hyperopic Children, Emmetropic Adolescents, and Young Adults: A Multicenter Quantitative Trait Study.

J Ophthalmol

Even though ocular refractive state is highly heritable and under strong genetic control, the identification of susceptibility genes remains a challenge. Several HGF (hepatocyte growth factor) gene variants have been associated with ocular refractive errors and corneal pathology.

Here, we assess the association of an HGF gene variant, previously reported as associated with hyperopia, and ocular biometric parameters in a multicenter Spanish cohort.

An observational prospective multicenter cross-sectional study was designed, including a total of 403 unrelated subjects comprising 188 hyperopic children (5 to 17 years) and 2 control groups: 52 emmetropic adolescents (13 to 17 years) and 163 emmetropic young adults (18 to 28 years). Each individual underwent a comprehensive eye examination including cycloplegic refraction, and topographic and ocular biometric analysis. Genomic DNA was extracted from oral swabs. HGF single nucleotide polymorphism (SNP) rs12536657 was genotyped. Genotypic, allelic, and logistic regression analyses were performed comparing the different groups. A quantitative trait association test analyzing several biometric parameters was also performed using generalized estimating equations (GEEs) adjusting for age and gender.

No association between rs12536657 and hyperopia was found through gender-adjusted logistic regression comparing the hyperopic children with either of the two control groups. Significant associations between mean topographic corneal curvature and rs12536657 for G/A (slope = +0.32; CI 95%: 0.04-0.60; p=0.023) and A/A (slope = +0.76; CI 95%: 0.12-1.40; p=0.020) genotypes were observed with the age- and gender-adjusted univariate GEE model. Both flat and steep corneal topographic meridians were also significantly associated with rs12536657 for the G/A and A/A genotypes. No association was found between rs12536657 and any other topographic or biometric measurements.

Our results support a possible role for HGF gene variant rs12536657 in corneal curvature in our population. To our knowledge, this is the first multicenter quantitative trait association study of HGF genotypes and ocular biometric parameters comprising a pediatric cohort.