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The latest medical news on Bile Duct Cancer

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Nature.com's Bile Duct Cancer

Advanced cholangiocarcinoma has a poor prognosis. Molecular targeted approaches have been proposed for patients after progression under first-line ...
Nature.com's Bile Duct Cancer

Cholangiocarcinoma (CCA) is a primary malignancy of the biliary tract with a dismal prognosis. Recently, several actionable genetic aberrations wer...
Nature.com's Bile Duct Cancer

Immunotherapy with immune checkpoint inhibitors (ICIs) is being explored to improve cholangiocarcinoma (CCA) therapy. However, it remains difficult...
Nature.com's Bile Duct Cancer

Nature.com's Bile Duct Cancer

The long culture duration of patient-derived organoids (PDOs) have severely limited their clinical applications. The aim of this study was to deter...
Nature.com's Bile Duct Cancer

The molecular classification and tumour microenvironment in intrahepatic cholangiocarcinoma (iCCA) need further characterisation. Here, the authors...
Nature.com's Bile Duct Cancer

WW domain-containing E3 ubiquitin protein ligase1 (WWP1) is reported to be upregulated in many types of human cancers; however, its expression and ...
Nature.com's Bile Duct Cancer

Aldehyde dehydrogenases (ALDHs) play an essential role in regulating malignant tumor progression; however, their role in cholangiocarcinoma (CCA) h...
Nature.com's Bile Duct Cancer

Intrahepatic cholangiocarcinoma (iCCA) has emerged as a promising candidate for precision medicine, especially in the case of activating FGFR2 gene...
Nature.com's Bile Duct Cancer

Circulating liver enzymes, like alanine aminotransferase (ALT) and aspartate aminotransferase (AST), are highly heritable and predictive of disease...
Nature.com's Bile Duct Cancer

Intrahepatic cholangiocarcinoma (IHCC) is a highly aggressive malignancy with a poor prognosis. It is thought to originate from cholangiocytes, whi...
Nature.com's Bile Duct Cancer

Advanced biliary tract cancer (ABC) has a poor prognosis. Cediranib, in addition to cisplatin/gemcitabine [CisGem], improved the response rate, but...