The latest medical research on Cosmetic Medicine

The research magnet gathers the latest research from around the web, based on your specialty area. Below you will find a sample of some of the most recent articles from reputable medical journals about cosmetic medicine gathered by our medical AI research bot.

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Liquid Spreader Grafts: Internal Nasal Valve Opening with Hyaluronic Acid.

Aesthetic Plastic Surgery

Nasal valve disorders frequently give rise to nasal obstruction. Dermal fillers could be used in the internal valve area to generate valve widening. The goal of this study was to report our "liquid spreader" procedure consisting in the injection of hyaluronic acid (HA) at the internal nasal valve in patients complaining of nasal obstruction.

The procedure described in this paper is suitable for patients with unilateral or bilateral nasal obstruction related to architectural features resulting in narrowing of the internal nasal valve. HA is injected along the internal valve from a single entry point located at the anterior part of the internal valve, thus creating a volume which will induce nasal valve widening. Rhinomanometries and visual analog scales (VAS) regarding nasal obstruction were collected before and after the procedure.

Sixteen patients were enrolled (7 females). Mean age was 44 years (min=24 y-o, max=65 y-o). Thirteen presented nasal valve narrowing without septal deviation while 3 patients had high septal deviation. Before injection, mean nasal resistances were 3.4±5.6 sPa/mL (min=0.55, max=19.8). One month after injection, mean nasal resistances were 0.38±0.26 sPa/mL (min = 0.20, max = 0.85). The difference was statistically significant (p=0.049). VAS scores were improved with a trend back to baseline after 12 months.

The liquid spreader is a useful procedure that can be combined with non-surgical esthetic rhinoplasties. Level of Evidence IV This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Cupid Lift: Advanced Lip Design using the Deep Plane Upper Lip Lift and Simplified Corner Lift.

Aesthetic Surgery Journal

The upper lip lift has been described using a variety of techniques over several decades, however many questions have remained unanswered regarding the benefits and drawbacks of each technique. The Deep Plane or Modified Upper lip lift procedure has been recently introduced to help mitigate risk and maximize outcomes. The CUPID Lip Lift design provides an additional formulary to guide the markings for the Deep Plane Lip Lift and provide more reproducible and successful outcomes.

To better characterize and simplify the complex and artistic decision-making process involved in the upper lip lift and corner lip lift. A mathematical guide is presented to maintain natural balance to the upper lip, optimizing muscle function, and when to add a corner lift. Design elements, aging and future treatment considerations are elucidated.

A PubMed search was performed in October 2021 by the primary author (BT) for all journal articles published regarding upper lip lift and corner lip lifts. The search was conducted from 1950 to present day in all languages and without exclusion criteria. Patient results and evolution of the deep plane upper lip lift design over 6 years was analyzed to provide a thorough discussion of elements to consider during lip lift design.

The deep plane upper lip design evolution has reached a point where a mathematical design may now be applied to an artistic concept. Following the patterns demonstrated in over 2440 consecutive lip lifts, we have been better able to understand the nuances involved in proper design that will avoid acceleration of aging, exaggeration of appearance, with a lower need for revision while maximizing results.

Upper lip lift design is more complex than most practitioners currently realize. This article outlines a mathematical concept that enables the practitioner to obtain more aesthetically pleasing and consistent outcomes. The modifications to this technique have largely been driven by desire to eradicate inadequacies as pointed out by patients. This novel approach to lip lift design enables the practitioner to improve lip balance, facial harmony, tooth show and obtain adequate exposure of the lateral vermillion.

Frontal-Temporal Triangle Area Hair for Eyebrow Restoration in Asians: A Comparative Study With Periauricular and Occipital Hair.

Dermatol Surg

The frontal-temporal triangle area (FTTA) hair has a slow growth rate and thin caliber, which are similar to those of eyebrow hair. However, a comparison of cosmetic outcomes between FTTA and other scalp hair grafts in eyebrow transplantation has not been performed.

To compare the cosmetic outcomes of FTTA hair and periauricular and occipital area (POA) hair in eyebrow restoration.

A retrospective analysis of 155 patients with FTTA or POA hair transplants was performed. Comparative variables included patient characteristics, hair density, diameter, percentage of one-hair follicular units (FUs), number of transplanted FUs, harvesting time, transection rate, hair survival rate, frequency of eyebrow trimming, and patient satisfaction.

There was a significant difference in hair density, diameter, percentage of one-hair FUs, and harvesting time between the FTTA and POA hair transplants. The FTTA hair grew significantly slower than the POA hair did. The patients in the FTTA group trimmed their postoperative eyebrows at a significantly longer interval than those in the POA group. The percentage of patients who were very satisfied with the surgery results was higher in the FTTA group.

The FTTA hair grafts can provide aesthetically pleasing cosmetic results in eyebrow restoration.

Cheek Donor Site for Full-Thickness Skin Graft Repair of the Nasal Ala: Outcomes of a Retrospective Cohort Study.

Dermatol Surg

Full-thickness skin grafts (FTSGs) are useful repairs for reconstructing nasal alar defects. Traditional donor sites include the preauricular, postauricular, and supraclavicular skin.

To evaluate esthetic outcomes and complications of nasal alar defects repaired with FTSGs from the medial cheek.

A retrospective chart review of Mohs surgery patients who had FTSG repair of the nasal ala between January 2015 and August 2020 was performed. Demographic, surgery, and follow-up visit data were reviewed. Cosmesis was rated by a facial plastic surgeon, a Mohs surgeon, and a plastic surgeon using baseline, defect, and follow-up visit photographs.

Sixty-nine patients with FTSG repairs of nasal alar defects were identified. 51 of 69 patients (73.9%) had the cheek donor site, and 18 of 69 patients (26.1%) had a noncheek donor site. The mean (SD) rater visual analog score for both cohorts was good with no significant difference (cheek: 65.9 [13.8]; noncheek: 66.1 [15.3]; p = .96). A notable difference in the complication rate by donor site was observed (cheek: 6.9%, noncheek: 16.7%; p = .13), although it did not reach significance.

The cheek is a reliable FTSG donor site for nasal alar defects after Mohs micrographic surgery, with a trend toward fewer complications.

Quantifying Skin Uptake of Topicals After 1,927-nm and 1,440-nm Nonablative Fractional Diode Laser Treatment.

Dermatol Surg

Although the stratum corneum limits transdermal absorption of topicals, laser devices can enhance topical uptake by disrupting the skin barrier. Nonablative lasers are commonly used, but their effects on topical uptake should be quantified to optimize outcomes.

The objective of this study is to analyze transdermal uptake of 4 topicals after nonablative fractional diode laser pretreatment.

Human donor tissue was pretreated ex vivo with a nonablative fractional diode laser (1,927 nm or 1,440 nm, at varying treatment densities, powers, and peak energies) followed by application of either 2% salicylic acid, 10% ascorbic acid, over-the-counter mineral eye serum, or 4% hydroquinone. Topical uptake was quantified over 24 hours.

Despite lower power settings, pretreatment with the 1,927 nm wavelength was associated with greater uptake of 10% ascorbic acid, mineral eye serum, and 4% hydroquinone than the 1,440 nm wavelength. In addition, 1,440-nm laser pretreatment with higher density (320 microscopic treatment zones [MTZ]/cm2) and peak power (3 W) was associated with similar uptake but greater retention of 2% salicylic acid and greater uptake of 10% ascorbic acid than that with lower density (80 MTZ/cm2) and peak power (1.2 W).

When using laser pretreatment, device settings should be adjusted to balance outcomes with potential side effects.

Primary cutaneous Rosai-Dorfman-Destombes disease with features mimicking IgG4-related disease: A challenging case report and literature review.

Australasian Journal of Dermatology

Rosai-Dorfman-Destombes disease (RDD) is a rare histiocytic disorder affecting lymph nodes as well as extranodal sites. Although cutaneous involvem...

A Modified Large-Cap Graft in East Asian Revision Rhinoplasty.

Aesthetic Plastic Surgery

Reconstructing a well-defined nasal tip is a big challenge for East Asian patients, especially with nasal tip irregularities or short noses in revision rhinoplasty. This study aims to report our experience with a modified large-cap graft for improving the contour of the nasal tip in revision rhinoplasty.

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Most patients reported satisfactory aesthetic outcomes with overall ROE score increasing from preoperative 11.66 ± 3.98 to postoperative 17.30 ± 5.03 (p < 0.001). The doctors' evaluations on the improved contour of the nose rendered an overall score of 3.77 ± 0.42. The complication rate was 3.3% (pleural tear, 1.1%; hypertrophic scar, 2.2%) at the donor site, and 7.7% at the recipient site (warping, 3.3%; extrusion, 1.1%; deviation, 2.2%; infection, 1.1%). No other complications were observed during follow-up.

Large-cap graft may be safe and efficient for reconstructing contour of the nasal tip in revision rhinoplasty for East Asian patients.

Complementary and integrative remedies in the treatment of chronic pruritus: A review of clinical trials.

J Cosmet Dermatol

Chronic pruritus is one of the most common conditions in dermatology as well as a common manifestation in many systemic diseases. Since the etiology of chronic pruritus remains somewhat unknown, hence, conventional medications may not always show a good therapeutic response. This finding has led both investigators and patients to use herbal and complementary remedies for its treatment. The aim of this study was to review clinical trials in which herbal and complementary medicine was used in the control and treatment of chronic pruritus.

In this study, we reviewed related articles in this domain, from 2000 to 2020. The search involved electronic databases including PubMed, Scopus, Web of Science, Cochrane, Google Scholar, and SID databases using the keywords "pruritus", "itch", "herb", "complementary medicine", "traditional medicine", "integrative medicine", and their related MeSH terms. Finally, we extracted the pertinent information from these articles and summarized the results.

The findings of this study showed that 17 clinical trials have been conducted to date in order to evaluate the efficacy of herbal remedies and complementary medicines in the treatment of chronic pruritus. Herbal remedies including turmeric, Fumaria parviflora, Avena sativa, capsaicin, sweet almond oil, peppermint oil, violet oil, vinegar, as well as manual therapies including aromatherapy, auricular acupressure and acupuncture, were significantly effective in the treatment of chronic pruritus.

There are only a few studies published on the therapeutic efficacy of herbal remedies and complementary medicine in the treatment of chronic pruritus. Some have shown promising results. Therefore, more evidence-based studies are needed in order to determine if herbal remedies and complementary medicine could be an effective alternative or adjuvant treatment modality in chronic pruritus.

Is there a lınk between alopecıa areata and gut?

J Cosmet Dermatol

There may be an association between increased intestinal permeability and the progression of alopecia areata (AA).

The present study aimed to investigate the role of intestinal permeability in the etiopathogenesis of AA and its association with the severity of the disease.

Serum zonulin levels of 70 patients with AA who were not receiving any systemic treatment and of 70 healthy control subjects were measured.

The median serum zonulin level in the patient group (46.38 ng/mL) did not differ significantly from that in the control group (50.34 ng/mL) (p = 0.828). Moreover, there was no significant relationship between serum zonulin levels and the severity of the disease (p = 0.549).

We did not observe an increase in intestinal permeability secondary to zonulin expression in patients with AA. However, in order to generalize this result to all patients with AA, serum zonulin levels need to be evaluated in studies including more patients with severe disease, AT, and AU.

2940- nm erbium:YAG laser versus 980- nm diode laser in the treatment of multiple seborrheic keratoses: A prospective comparative randomized study.

J Cosmet Dermatol

Seborrheic keratoses (SKs) are the most common benign epithelial tumors encountered in clinical practice. Complications associated with traditional treatments of SKs, urge the scientists to seek alternative treatment modalities.

To compare the efficacy and safety of 2940 -nm erbium- doped yttrium aluminum garnet (Er:YAG) laser versus 980- nm diode laser both clinically and dermoscopically for the treatment of seborrheic keratosis.

Thirty subjects with multiple SKs were randomized to receive two sessions of either Er:YAG laser (n=15) or diode laser (n=15) and were followed-up for 2 weeks after each session, and at 3 and 6 months after the second session.

Both lasers exhibited significant clearance of SKs with no significant difference in clinical and dermoscopic improvement between the two systems. However, Er:YAG laser showed shorter total downtime but more serious erythema, while scarring and hyperpigmentation were observed in diode laser group. No recurrence was detected in both groups at 6 months follow-up.

Er:YAG and diode lasers both are effective, non- invasive and well-tolerated techniques in treatment of SKs.

Super-selective intra-arterial dissolution therapy for lingual artery occlusion resulting due to the use of hyaluronic acid for chin augmentation: The first reported case.

J Cosmet Dermatol

As a consequence of the current trend of performing minimally invasive surgery, the use of injectable fillers has progressively increased in aesthe...

Morphological parameters predicting subthreshold micropulse laser effectiveness in central serous chorioretinopathy.

Lasers in Medical Science

The purpose of this prospective study was to predict the effectiveness of subthreshold micropulse laser (SML) based on morphological parameters in patients with central serous chorioretinopathy (CSC).

Thirty-one patients were examined at presentation, 3 months, and 6 months after the disease onset. In patients with persistent subretinal fluid (SRF) at 3 months, SML was performed. The following morphological parameters were observed just before treatment: central retinal thickness (CRT), maximal SRF, choroidal thickness (CT), pigment epithelial detachment (PED) height and width, number of hyperreflective foci (HF) at fovea and leakage site, secondary choroidal neovascularization (CNV), and severity of retinal pigment epithelium (RPE) alterations using multimodal imaging.

Good response was associated with lower SRF (p = 0.038), narrower PED (p = 0.078), and decreasing number of HF at fovea (difHFf) (p = 0 .016) just before the treatment. From a bivariate and multivariate point of view, the two groups differed significantly in the pair (SRF, PED width) (p = 0.048) and in the triple (SRF, PED width, difHFf) (p = 0.026).

Lower SRF, narrower PED, and decreasing HF could be associated with good response to SML in CSC patients.