The latest medical research on Neurodevelopmental Disabilities
The research magnet gathers the latest research from around the web, based on your specialty area. Below you will find a sample of some of the most recent articles from reputable medical journals about neurodevelopmental disabilities gathered by our medical AI research bot.
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Request AccessParents and service providers' perspectives about social inclusion of people with neurodevelopmental disabilities in Qatar: investigation of financial transactions and personal status laws.
International Journal of EpidemiologyThe current study aims to explore parents and service providers' attitudes towards the social inclusion of people with neurodevelopmental disabilit...
Perceptions of Saudi elementary school special education teachers regarding mathematics content and instructional practices for students with intellectual disabilities.
International Journal of EpidemiologyThis study explored the perceptions of special education teachers of students with intellectual disabilities at three elementary schools in Saudi A...
Exploring parental use of social media among autism spectrum disorder families in the UAE: perspectives and challenges in fostering social inclusion.
International Journal of EpidemiologyThis study examines the parental use of social media within autism spectrum disorder (ASD) families in the United Arab Emirates (UAE), focusing on ...
Family quality of life of caregivers of individuals with autism, with other disabilities, and without disabilities: the case of Saudi Arabia.
International Journal of EpidemiologyThis comprehensive study delves into the family quality of life (FQOL) of caregivers in Saudi Arabia, focusing on those caring for individuals with...
Diet and physical activity modification: impact on adaptive behavior and biochemical measures of children with Down syndrome.
International Journal of EpidemiologyObesity in children with Down syndrome (DS) has negative implications for behavior. The aim was to assess the influence of weight reduction by diet modification with and without physical therapy sessions on adaptive behavior and some biochemical measures in children with DS with obesity.
The study included 100 children with DS (56 males, 44 females; age range: 6-9 (8.5 ± 1.7) years. They were subjected to history taking, clinical examination, and the Vineland adaptive behavior scale. They were randomly divided into two groups: Group I underwent nutritional modification, and Group II was subjected to an added exercise program. The biochemical measures were estimated using the automated chemistry analyzer for blood chemistry (lipids), or ELISA.
An elevation of behavioral adaptive scores was noticed after the weight reduction, together with a reduction in the levels of triglycerides and an elevation of high-density lipoprotein-C levels. Levels of interleukin I, interleukin 6, and leptin were reduced in both groups. However, the improvement regarding the estimated measures was greater in Group II (p < 0.05).
Weight reduction in children with DS was beneficial for their adaptive behavior and for adjusting dyslipidemia, along with some measures of inflammation. Combining physical activity with nutritional modification would help in the better advancement of the health and adaptive behavior of children with DS associated with obesity compared with isolated nutritional modification.
The mediating role of emotional regulation and emotional expression in the relationship between autistic traits and empathy in Saudi students.
International Journal of EpidemiologyThe aim was to investigate the mediating role of emotional regulation and emotional expression in the relationship between autistic traits and empa...
Social inclusion of children with autism spectrum disorders and mothers' mental health in two Arabic-speaking countries: a mediational model of culture and resilience.
International Journal of EpidemiologyMothers of children with autism spectrum disorders (ASDs) have been reported to be more likely to experience lower levels of mental health as a result of the increased challenges associated with care provision and social inclusion of their children. Social inclusion in Arab countries differs in terms of quality and practices due to ecological and cultural variations. Based on an expected impact of culture and resilience, this study investigated the relationship between social inclusion practices and mothers' mental health in two Arabic-speaking countries.
A total sample of 660 mothers of children with ASD from Oman and Egypt participated in the study and were administered measures of perceived social inclusion practices, mental health, and resilience.
Multi-group path analyses showed that culture and resilience have an impact on the association between social inclusion practices and mothers' mental health.
Our findings have significant implications for social inclusion practices. They underscore the need to build mothers' resilience to improve their mental health. Additionally, social inclusion practices need to be prioritized by policy makers and professionals in Arab countries in order to develop a model of best practices of social inclusion across Arab countries.
Social entrepreneurship - inclusive disability employment in the UAE.
International Journal of EpidemiologyThis paper explored the transition of a disability inclusive employment programme in a private landscaping company into a standalone social enterpr...
The effectiveness of a training program based on the assessment of basic language and learning skills- revised tool 'ABLLS-R' in reducing stereotyped behaviors among children with autism spectrum disorder.
International Journal of EpidemiologyThis study investigates the efficiency of a developed training program based on ABLLS-R in reducing stereotypical behaviors among children with aut...
Parent input: shaping inclusive education for students with disabilities.
International Journal of EpidemiologyOver the past 20 years, significant developments have occurred in Jordan to create more inclusive school settings. This is in part due to new natio...
Investigating social orienting in children with Phelan-McDermid syndrome and 'idiopathic' autism.
Journal of Neurodevelopmental DisordersNA.
This study used a semi-naturalistic task to explore orienting to social versus non-social stimuli and its relation to clinical features in individuals diagnosed with PMS, autism, and neurotypical children recruited in the United States and the United Kingdom.
At the group level, autistic and neurotypical children responded on average more often to social than non-social stimuli, while children with PMS responded similarly to both stimulus types. Both clinical groups responded significantly less often to social stimuli than neurotypical children. In addition, we found considerable variability in orienting responses within each group that were of clinical relevance. In the autism group, non-social orienting was associated with mental age, while in the PMS group social and non-social orienting were related to strength of autistic features.
These findings do not support specific social motivation difficulties in either clinical group. Instead, they highlight the importance of exploring individual differences in orienting responses in Phelan-McDermid Syndrome in relation to autistic features.
Systemic Postnatal Corticosteroids, Bronchopulmonary Dysplasia, and Survival Free of Cerebral Palsy.
Cerebral Palsy- importance
- objective
- design, setting, and participants
- interventions
- main outcomes and measures
- results
- conclusions and relevance
Systemic postnatal corticosteroids have been shown to reduce rates of bronchopulmonary dysplasia (BPD) in infants born preterm, but both corticosteroids and BPD are associated with cerebral palsy.
To describe how the association between systemic postnatal corticosteroids and survival free of cerebral palsy varies with the risk of BPD in infants born preterm, and if the association differs between dexamethasone and hydrocortisone, or with age at starting treatment.
This comparative effectiveness research used weighted meta-regression analysis of eligible randomized clinical trials (RCTs) of systemic postnatal corticosteroids reported from June 1989 through March 2022 that included rates of all of BPD, mortality, and cerebral palsy in neonatal intensive care units in 10 countries. Infants born preterm at risk of BPD were included. Data were analyzed from April and July 2024.
Systemic dexamethasone or hydrocortisone.
Type and timing of corticosteroid, control group rate of BPD, and risk difference in survival free of cerebral palsy between corticosteroid and control arms.
Twenty-six RCTs with data on 3700 randomized infants were eligible; 18 (69%) investigated dexamethasone and 8 (31%) hydrocortisone; 12 (46%) started treatment in the first week after birth. There was evidence for a differential association of the type of corticosteroid with the effect of systemic dexamethasone on survival free of cerebral palsy and the risk of BPD in control groups (interaction coefficient, 0.54; 95% CI, 0.25-0.82; P = .001). For dexamethasone, for every 10-percentage point increase in the risk of BPD, the risk difference for survival free of cerebral palsy increased by 3.74% (95% CI, 1.54 to 5.93; P = .002). Dexamethasone was associated with improved survival free of cerebral palsy at a risk of BPD greater than 70%. Conversely, dexamethasone was associated with harm at a risk of BPD less than 30%. There was some evidence for a negative association with hydrocortisone, with possible benefit with risk of BPD less than 30%. There was no strong evidence for a differential effect of timing among those treated with dexamethasone (interaction coefficient, 0.13; 95% CI, -0.04 to 0.30; P = .14).
The findings suggest that dexamethasone (compared with control) was associated with improved rates of survival free of cerebral palsy in infants at high risk of BPD but should be avoided in those at low risk. A role for hydrocortisone is uncertain.
