The latest medical research on Haematology

The research magnet gathers the latest research from around the web, based on your specialty area. Below you will find a sample of some of the most recent articles from reputable medical journals about haematology gathered by our medical AI research bot.

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Post Transplant Lymphoproliferative Disorder.

Indian Journal Hematology Blood Transfusion

Posttransplant lymphoproliferative disorder is an extremely fatal complication arising in transplant recipients as a side effect of immunosuppressi...

Eltrombopag: Role in Cytopenias Following Hematopoietic Stem Cell Transplantation.

Indian Journal Hematology Blood Transfusion

Eltrombopag is a small molecule oral agonist of the thrombopoietin receptor. Initially used for improving thrombocytopenia in chronic immune thromb...

"Hairy Cell Leukemia (HCL): 'Real World' Outcome".

Indian Journal Hematology Blood Transfusion

HCL is an uncommon B cell lympho-proliferative disorder with high remission rates. There is paucity of data on the long-term outcome of HCL from In...

Conventional Cytogenetics and Interphase Fluorescence In Situ Hybridization Results in Multiple Myeloma: A Turkey Laboratory Analysis of 381 Cases.

Indian Journal Hematology Blood Transfusion

Multiple myeloma (MM) is an uncontrolled proliferation of plasma cells and these cells play an important role in the immune system. In this researc...

Inherited Bleeding Disorders in North Indian Children: 14 years' Experience from a Tertiary Care Center.

Indian Journal Hematology Blood Transfusion

Inherited bleeding disorders are not uncommon in pediatric practice: most of them being chronic, require lifelong replacement therapy. To frame a m...

Promising Response to Thalidomide in Symptomatic β-Thalassemia.

Indian Journal Hematology Blood Transfusion

Over the past decade, few reports suggested that the drug thalidomide (HbF inducer) may be of value in a subset of transfusion-dependent and non-tr...

Validation of Point of Care Hemoglobin Estimation Among Pregnant Women Using Digital Hemoglobinometers (HemoCue 301 and HemoCue 201+) as Compared with Auto-Analyzer.

Indian Journal Hematology Blood Transfusion

Accurate and reliable point of care tests (POCTs) for hemoglobin estimation is essential for early diagnosis and management of anemia. This study w...

Specific Combinations of Erythrocyte Group Antigens in Blood Donors.

Indian Journal Hematology Blood Transfusion

Blood groups are inherited biological characteristics that do not change throughout life only in healthy people. Blood group antigens determine the...

Forecasting the Amount of Blood Ordered in the Obstetrics and Gynaecology Ward with the Data Mining Approach.

Indian Journal Hematology Blood Transfusion

Preoperative blood ordering is frequently used in the obstetrics and gynecology ward of university hospitals in Iran, even for surgeries that rarel...

Activity Wise Unit Cost of Blood Components in a Tertiary Care Hospital Blood Bank for the Year 2018.

Indian Journal Hematology Blood Transfusion

The present study on cost of a unit of blood was conducted in blood bank of a tertiary care public hospital with an annual collection of 20,748. A ...

Azacytidine in Newly Diagnosed FLT3-ITD-Positive Acute Myeloid Leukemia Presenting with Pneumonia: A Case Series.

Indian Journal Hematology Blood Transfusion

Acute myeloid leukemia (AML) is an aggressive disease that predisposes the patients to infections. FMS-like tyrosine kinase 3 internal tandem dupli...

Nasal-Type Extranodal Natural Killer/T Cell Lymphoma with Meningeal Involvement: A Case Report and Literature Review.

Indian Journal Hematology Blood Transfusion

We report a case of a 26-year-old man diagnosed with nasal-type extranodal natural killer/T cell lymphoma (ENKTL) extending beyond the nasal cavity. Complete response was achieved after therapy, followed by rapid metastasis to the meningeal nerve fibres. The overall survival (OS) of the patient was 15 months. To better understand ENKTL with meningeal involvement, we summarized the clinical features of the 10 cases involving meningeal metastasis in ENKTL reported in the English literature.

The patient was admitted for the ENKTL diagnosis, and positron emission tomography-computed tomography showed the disease stage and response. When central nervous system (CNS) infiltration was suspected, magnetic resonance imaging (MRI) of the brain and spinal cord was performed, as well as cerebrospinal fluid (CSF) analysis with flow cytometric immunophenotyping.

MRI of the brain and spinal cord revealed normal results. CSF analysis with flow cytometric immunophenotyping showed NK/T lymphoma cell infiltration.

Meningeal metastasis of ENKTL is rare; when patients present with nervous system symptoms, CNS metastasis should be considered as a possibility, even in the early stage. The OS of our patient was 15 months, which is the longest survival time reported in the literature, probably due to early diagnosis and comprehensive management, including intrathecal therapy, chemotherapy and radiotherapy of the whole brain and spinal cord.