The latest medical research on Pharmacy

The research magnet gathers the latest research from around the web, based on your specialty area. Below you will find a sample of some of the most recent articles from reputable medical journals about pharmacy gathered by our medical AI research bot.

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Theophylline for Spinal Cord Injury Associated Bradycardia.

Journal of Pharmacy and Pharmacology

Spinal cord injury (SCI) related bradycardia occurs frequently in patients with high cervical spine injuries. In patients with SCI-related symptomatic bradycardia, a variety of agents have been used to improve heart rate and reduce the need for vasopressor therapy. The literature concerning the use of theophylline in this disease state is sparse.

The primary objective of this study was to evaluate and describe the use of theophylline for SCI-related symptomatic bradycardia.

This was a retrospective case series of patients with SCI-related symptomatic bradycardia who were treated with theophylline. Patients were evaluated based on clinical response to theophylline. Patients were classified as a responder if vasopressors were discontinued or the number of bradycardia episodes decreased following the initiation of theophylline.

A total of twenty-six patients were included in the study. 17 (65.4%) patients were classified as responders, 5 (19.2%) patients were classified as non-responders, and 4 (15.4%) of patients were classified as undetermined. 11 patients (43.31%) were discharged on theophylline with 7 of these patients (41.2%) classified as responders. There were no significant differences between those classified as responders and those who were not.

This case series suggest that theophylline could be used as adjunctive therapy in patients with bradycardia secondary to acute SCI who achieve an adequate response to theophylline.

Key Points for Pharmacists From the ACC Expert Consensus Decision Pathway for Patients Hospitalized With Heart Failure.

Journal of Pharmacy and Pharmacology

Heart failure (HF) is a complex condition, and its clinical course often includes periods of decompensation that represent a deterioration in clini...

Risk factors for clinically relevant deviations in patients' medication lists reported by patients in personal health records: a prospective cohort study in a hospital setting.

International Journal of Epidemiology

Background Personal health records have the potential to identify medication discrepancies. Although they facilitate patient empowerment and broad ...

Deprescribing clonazepam in primary care older patients: a feasibility study.

International Journal of Epidemiology

Background Inappropriate use of clonazepam by older adults is associated with cognitive impairment, delirium, and falls. Strategies to optimize its...

Cost-effectiveness of check of medication appropriateness: methodological approach.

International Journal of Epidemiology

Background Adverse drug events following inappropriate prescribing in the hospital cause a substantial and avoidable medical and economic burden to...

Diagnosis and management of acute coronary syndromes.

Australian Prescriber

Acute coronary syndromes are a significant cause of morbidity and mortality in Australia. Outcomes are likely to be improved by rapid and accurate ...

Medical abortion in primary care.

Australian Prescriber

Early medical abortion is a safe, cost effective and acceptable alternative to surgical abortion. It offers privacy and autonomy and can be provide...

Testing for cirrhosis.

Australian Prescriber

Cirrhosis can be suspected by a thorough clinical assessment, but compensated liver disease is often asymptomatic. Select investigations are theref...

Investigating thyroid nodules.

Australian Prescriber

Thyroid nodules are common clinically and even more common as an incidental finding during ultrasonography. Routine screening of thyroid nodules in...

Erratum: The safety of commonly used vitamins and minerals [Correction].

Australian Prescriber

[This corrects the article DOI: 10.18773/austprescr.2021.029.].

Assessing community pharmacists' attitudes towards identifying opportunities for deprescribing in clinical practice in Ireland.

International Journal of Epidemiology

The main objective of this study was to assess community pharmacists' thoughts regarding the role they can play in effectively integrating deprescribing into clinical practice in Ireland. The aim was to assess pharmacists' (1) knowledge of deprescribing, (2) confidence in deprescribing, (3) attitudes towards deprescribing and (iv) barriers and facilitators to deprescribing in a community pharmacy setting.

An online questionnaire was disseminated to pharmacists currently registered with the Pharmaceutical Society of Ireland, with instruction only to complete if working in community pharmacy. Statistical analysis was conducted on the quantitative data, whereas thematic analysis was carried out on the open-ended responses.

Results indicate good knowledge scores and positive attitudes surrounding deprescribing, with demographic factors having no significant effect on results. Although deprescribing knowledge is high, willingness to engage is hindered by obstacles such as time. Remuneration was identified as an enabler for deprescribing. Interdisciplinary educational opportunities and bidirectional communication channels with prescribers are viewed as the major facilitators of deprescribing.

Community pharmacists demonstrate that they possess sufficient knowledge, confidence and willingness to play a greater role in facilitating deprescribing. To enable this role expansion, enablers such as education and funding need to be implemented, to overcome barriers such as insufficient time. Further studies are required to assess community pharmacists' deprescribing competence, to demonstrate their ability to fulfil this role in clinical practice in Ireland.

Acute Portal and Superior Mesenteric Vein Thrombosis with Topical Testosterone Therapy: An Adverse Drug Event Case Report.

Journal of Pharmacy and Pharmacology

This is a case report of a 55-year-old Caucasian male prescribed topical testosterone therapy for 12 months prior to admission, when he was diagnos...