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The latest medical research on Diabetes Mellitus

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Association between preconception body mass index and fertility in adult female: A systematic review and meta-analysis.

Obesity Reviews

Obesity potentially reduces fertility, but systematic reviews are lacking to summarize the existing literature. Therefore, we systematically summar...

Leptin is a potential biomarker of childhood obesity and an indicator of the effectiveness of weight-loss interventions.

Obesity Reviews

Childhood obesity represents a significant public health concern, imposing a substantial burden on the healthcare system. Furthermore, weight-loss ...

Attention-deficit/hyperactivity disorder in adolescent and adult candidates for metabolic and bariatric surgery: A systematic review and meta-analysis.

Obesity Reviews

Attention-deficit with hyperactivity disorder (ADHD) is associated with obesity and impacts the outcome of metabolic and bariatric surgery (MBS). This study aimed at calculating the prevalence in candidates for MBS, which is yet unclear.

We conducted a systematic review and meta-analysis, searching three databases from their respective inception to December 2022 for studies reporting the prevalence of ADHD in adolescents and adults assessed before undergoing MBS. The protocol was registered in PROSPERO (CRD42022384914). We adhered to Meta-analysis of Observational Studies in Epidemiology (MOOSE) and Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines; the quality of studies was assessed with the JBI Critical Appraisal checklist. Random-effect meta-analyses were performed; confidence intervals were computed with a binomial exact method, and the pooled estimate was calculated after double arcsine transformation.

Fourteen studies (24,455 adults) and three studies (299 adolescents) were selected. The quality of studies was moderate to poor; meta-analyses were performed on subgroups according to the case definition used. The prevalence is 8.94% and 9.90% in adults, and 28.73% in adolescents.

ADHD is three times more frequent in adults and six times more frequent in adolescents than in the general population. Recommendations are provided to improve the quality of future studies and obtain more reliable estimates of prevalence.

The most optimal school recruitment strategies for school-based obesity prevention and health promotion research in the United States: A systematic review with Delphi study.

Obesity Reviews

This systematic review with the Delphi study aimed to identify effective and resource-efficient (optimal) strategies for recruiting schools into he...

Trapped fat: Obesity pathogenesis as an intrinsic disorder in metabolic fuel partitioning.

Obesity Reviews

Our understanding of the pathophysiology of obesity remains at best incomplete despite a century of research. During this time, two alternative per...

Association between ultraprocessed food consumption and excess adiposity in children and adolescents: A systematic review.

Obesity Reviews

Ultraprocessed foods (UPF) consumption is associated with excess adiposity in adults, but this linkage remains unclear among children and adolescen...

Medical semiology of patients with monogenic obesity: A systematic review.

Obesity Reviews

Patients with monogenic obesity display numerous medical features on top of hyperphagic obesity, but no study to date has provided an exhaustive de...

Mitochondrial puzzle in muscle: Linking the electron transport system to overweight.

Obesity Reviews

Human skeletal muscle mitochondria regulate energy expenditure. Research has shown that the functionality of muscle mitochondria is altered in subj...

Efficacy and safety of once-weekly subcutaneous semaglutide on weight loss in patients with overweight or obesity without diabetes mellitus-A systematic review and meta-analysis of randomized controlled trials.

Obesity Reviews

Semaglutide is found to be efficient for weight loss in patients with overweight or obesity with diabetes mellitus (DM). With a wide range of adver...

The role of metabolic and bariatric surgery on the obesity pandemic in Latin America: A review of current practices and future directions.

Obesity Reviews

Latin America faces a significant public health challenge due to the high prevalence of obesity and its associated diseases. Metabolic and bariatri...

Effects of bariatric surgery on muscle strength and quality: A systematic review and meta-analysis.

Obesity Reviews

Obesity is a major health burden worldwide. Although bariatric surgery (BS) is recognized as an effective strategy for weight loss and comorbiditie...

A systematic review and qualitative synthesis of weight management interventions for people with spinal cord injury.

Obesity Reviews

People with spinal cord injury (SCI) are at greater risk of developing obesity and related co-morbidities than those without SCI. The objectives of...