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The latest medical research on Testicular Cancer

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Cordycepin induced MA-10 mouse Leydig tumor cell apoptosis by regulating p38 MAPKs and PI3K/AKT signaling pathways

Nature's Testicular Cancer

The p38 MAPKs play important roles in the regulation of balance between cell survival and cell death on the development of various cancers. However...

Effect Of Microgravity On Aromatase Expression In Sertoli Cells

Nature's Testicular Cancer

Cytochrome P450-aromatase catalyzes estrogen biosynthesis from C19 steroids. In the testis, Sertoli cells express P450-aromatase and represent the ...

Shared and unique genomic structural variants of different histological components within testicular germ cell tumours identified with mate pair sequencing

Nature's Testicular Cancer

Post-pubertal testicular germ-cell tumours (TGCTs) can present with a variety of distinct histologies which are nevertheless lineage related and of...

Ectopic miR-975 induces CTP synthase directed cell proliferation and differentiation in Drosophila melanogaster

Nature's Testicular Cancer

CTP synthase (CTPSyn) is an essential metabolic enzyme, synthesizing precursors required for nucleotides and phospholipids production. Previous stu...

miRNA-302s may act as oncogenes in human testicular germ cell tumours

Nature's Testicular Cancer

Testicular germ cell tumour (TGCT) represents the most common malignancy in young men in large parts of the world, but the aetiology is yet unclear...

Pan-cancer analyses of human nuclear receptors reveal transcriptome diversity and prognostic value across cancer types

Nature's Testicular Cancer

The human nuclear receptor (NR) superfamily comprises 48 ligand-dependent transcription factors that play regulatory roles in physiology and pathop...

Establishment and characterisation of testicular cancer patient-derived xenograft models for preclinical evaluation of novel therapeutic strategies

Nature's Testicular Cancer

Testicular cancer (TC) is the most common solid tumour in young men. While cisplatin-based chemotherapy is highly effective in TC patients, chemore...

The potential role of MR based radiomic biomarkers in the characterization of focal testicular lesions

Nature's Testicular Cancer

How to differentiate with MRI-based techniques testicular germ (TGCTs) and testicular non-germ cell tumors (TNGCTs) is still under debate and Radio...

Indications, feasibility and outcome of robotic retroperitoneal lymph node dissection for metastatic testicular germ cell tumours

Nature's Testicular Cancer

Data on robotic retroperitoneal lymph node dissection (R-RPLND) for metastatic testicular germ cell tumours (mTGCTs) are scarce and the use of R-RP...