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The latest medical research on Neuroendocrine Tumors

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Friend or foe? Deciphering androgen receptor action to improve bipolar androgen therapy for prostate cancer.

Neuroendocrine Tumors

Inhibiting the activity of the androgen receptor (AR) is the cornerstone treatment for advanced prostate cancer. AR-targeted therapies are highly e...

The complex landscape of luminal breast cancer.

Neuroendocrine Tumors

The breast epithelium, vital for mammary gland function, is influenced by oestrogen through the ER signalling pathway. Luminal breast cancer, chara...

Living with a RET gene mutation: patient perspectives.

Neuroendocrine Tumors

Multiple endocrine neoplasia type 2 (MEN2) is the collective term for 2 distinct types of autosomal dominantly inherited neuroendocrine neoplasm (N...

Chromosomal Alteration Patterns in PitNETs: Massive Losses in Aggressive Tumors.

Neuroendocrine Tumors

The molecular biology of pituitary neuroendocrine tumors (PitNETs) revealed few recurrent mutations and extensive chromosomal alterations, with the...

Cellular Mechanisms of RET Receptor Dysfunction in Multiple Endocrine Neoplasia 2.

Neuroendocrine Tumors

REarranged during Transfection (RET) is a developmentally important receptor tyrosine kinase that has been identified as an oncogenic driver in a n...

In Memoriam: Charis Eng, M.D., Ph.D. (1962-2024).

Neuroendocrine Tumors

Matthew Ringel On behalf of the entire editorial team of Endocrine-Related Cancer, and personally as trainees and collaborators who at present serv...

Mechanisms of RET mediated signal transduction.

Neuroendocrine Tumors

The RET receptor tyrosine kinase is physiologically stimulated by growth factors belonging to the glial cell line-derived neurotrophic factor (GDNF...

AGO2 protein: a key enzyme in the miRNA pathway as a novel biomarker in adrenocortical carcinoma.

Neuroendocrine Tumors

Adrenocortical carcinoma (ACC) is a rare and aggressive malignancy characterised by diagnostic challenges, high recurrence rates, and poor prognosi...

Genotype/phenotype correlations in multiple endocrine neoplasia type 2.

Neuroendocrine Tumors

Multiple endocrine neoplasia type 2 (MEN 2) is a rare hereditary endocrine tumour syndrome caused by mutations in the rearranged during transfectio...

Reappraisal of BRAFK601E-positive thyroid tumors in the NIFTP era.

Neuroendocrine Tumors

BRAFK601E is an uncommon mutation typically found in encapsulated follicular-patterned thyroid tumors. Previous studies on BRAFK601E-positive thyro...

Cutoff value of thyroglobulin in needle aspirates for screening neck masses of thyroid carcinoma.

Neuroendocrine Tumors

Measurement of thyroglobulin in fine needle aspirates (FNA-Tg) is useful for the diagnosis of lymph node metastasis in thyroid carcinoma; however, ...

Body composition in recurrent prostate cancer and the role of steroidogenic genotype.

Neuroendocrine Tumors

Hormone therapy (HT) to treat prostate cancer is reported to cause adverse changes in body composition. Clinically, interpatient body composition c...